莎拉（丹妮尔·帕娜贝克 Danielle Panabaker 饰）是一个轻松到有些纯粹的女孩，陷入了和有妇之夫泰瑞（安德鲁·霍华德 Andrew Howard 饰）的感情胶葛之中。然而，让莎拉莫得臆度的是，镇日，泰瑞竟然在毫无预兆的状态下将她霸道的遗弃了。莎拉的同事露（妮可·拉里贝特 Nicole LaLiberte 饰）不忍心顾念想臆度至友这样难过，因而把她带到酒吧买醉，在那里，两人重逢了名为西...
As John T. Wrecker continues his task of protecting a group of refugees from a virus, the threat of something new and even more dangerous grows ever closer in the form of monstrous mutants...